WebFeb 17, 2016 · SH-SY5Y neuroblast-like cells are a subclone of the parental neuroblastoma cell line SK-N-SH. The parental cell line was generated in 1970 from a bone marrow biopsy that contains both neuroblast-like and epithelial-like cells 15. SH-SY5Y cells have a stable karyotype consisting of 47 chromosomes, and can be differentiated from a neuroblast-like ... WebDynasore is a noncompetitive inhibitor of GTPases with the IC50 value of 15 μM [1] [2]. GTPases (singular GTPase) are hydrolase enzymes that play an important role in GTP binding and hydrolyzing. GTPases involve in …
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WebSH-SY5Y cells are a dopaminergic cell line commonly used as a model for neurodegenerative diseases. Parkinson’s disease is characterized by a loss of dopamine signaling as a result of dopaminergic cell death within the substantia nigra. Manganism is an idiopathic Parkinsonism-like disease caused by an accumulation of manganese in cells … WebMar 16, 2024 · Dynasore inhibits BMP2-induced increases of SH-SY5Y neurite length and branching. Abstract Bone morphogenetic protein 2 (BMP2) is a neurotrophic factor which … how does coal turn into diamond
Endocytosis contributes to BMP2-induced Smad …
WebSH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from a bone marrow biopsy taken from a four-year-old female with neuroblastoma.SH-SY5Y cells are often used as in vitro models of neuronal function and differentiation. They are adrenergic in phenotype but also … WebSH-SY5Y cells were transfected with si-ACSL4 or si-NC for 24 h and treated with 4.1% sev for 6 h, and then tested for the expression of AMPK, pAMPK, mTOR, and p-mTOR using western blot. (A) Representative images for western blot of AMPK, pAMPK, mTOR, and p-mTOR expression in SH-SY5Y cells are shown. ... WebThe SH-SY5Y human neuroblastoma cell line (ATCC® CRL-2266™) is one of the most used cell lines in neurosciences, either undifferentiated or differentiated into neuron-like cells. This review presents the characteristics of the SH-SY5Y cell line and proposes the results of a systematic review of literature on the use of this in vitro cell ... how does coal plant work